Combined polymorphisms in UDP-glucuronosyltransferases 1A1 and 1A6: implications for patients with Gilbert's syndrome

The Genetic Basis of the Reduced Expression of Bilirubin UDP-Glucuronosyltransferase 1 in Gilbert's Syndrome

Piter J. Bosma, Jayanta Roy Chowdhury, Conny Bakker et al. · New England Journal of Medicine · 1995 · 1.5K citations

Medicine, Genetics, Molecular Genetics +11

Racial variability in the UDP-glucuronosyltransferase 1 ( <i>UGT1A1</i> ) promoter: A balanced polymorphism for regulation of bilirubin metabolism?

Ernest Beutler, Terri Gelbart, Anna Demina · Proceedings of the National Academy of Sciences · 1998 · 852 citations · Full text

Life Sciences, Genetics, Molecular Genetics +11

Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis.

Yukio Ando, Hideo Saka, Maki Ando et al. · PubMed · 2000 · 788 citations

Medicine, Genetics, Pharmacology +15

Genetic variation in bilirubin UDP-glucuronosyltransferase gene promoter and Gilbert's syndrome

Gemma Monaghan, Máirín Ryan, Robert Hume et al. · The Lancet · 1996 · 589 citations

Life Sciences, Genetics, Molecular Genetics +8

Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism

Lalitha Iyer, Diana Hall, Sudip Das et al. · Clinical Pharmacology & Therapeutics · 1999 · 353 citations

Veterinary Medicine, Genetics, Molecular Genetics +15