Concepedia

Development of a semi-automated LC/MS/MS method for the simultaneous quantitation of 14,15-epoxyeicosatrienoic acid, 14,15-dihydroxyeicosatrienoic acid, leukotoxin and leukotoxin diol in human plasma as biomarkers of soluble epoxide hydrolase activity in vivo

Penny Zhu, Brian Peck, Hermes Licea‐Perez, James F. Callahan, Catherine Booth-Genthe

Journal of Chromatography B · 2011 · 17 citations · 21 references

DOI

Concepts

References

21

Cytochrome P450 2C is an EDHF synthase in coronary arteries

Beate Fißlthaler, Rüdiger Popp, Ladislau Kiss et al. · Nature · 1999 · 910 citations

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Cytochrome P450 and arachidonic acid bioactivation: molecular and functional properties of the arachidonate monooxygenase

Jorge H. Capdevila, John R. Falck, Raymond C. Harris · Journal of Lipid Research · 2000 · 555 citations · Full text

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Soluble Epoxide Hydrolase Inhibition Lowers Arterial Blood Pressure in Angiotensin II Hypertension

John D. Imig, Xueying Zhao, Jorge H. Capdevila et al. · Hypertension · 2002 · 401 citations · Full text

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Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase

Mehran F. Moghaddam, David F. Grant, Jeffrey M. Cheek et al. · Nature Medicine · 1997 · 310 citations · Full text

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An Orally Active Epoxide Hydrolase Inhibitor Lowers Blood Pressure and Provides Renal Protection in Salt-Sensitive Hypertension

John D. Imig, Xueying Zhao, Constantine Z. Zaharis et al. · Hypertension · 2005 · 256 citations · Full text

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