Concepedia

Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase

Mehran F. Moghaddam, David F. Grant, Jeffrey M. Cheek, Jessica F. Greene, Kristin C. Williamson, Bruce D. Hammock

Nature Medicine · 1997 · 310 citations · 29 references

Open access

Concepts

Life SciencesPharmacologyToxicologyBiochemical ToxicologyEnzymologyMechanisms Of ToxicityCellular ToxicologyLipid PeroxidationMechanisms Of Toxic InjuryMolecular Mechanisms Of ToxicityOxidative Damage To BiomoleculesReactive Oxygen SpeciesEnzymatic Toxin ActivityEpoxide Hydrolase ActivityEpoxide Hydrolase PathwaysEpoxide HydrolasesEpoxide Metabolites

References

29

Estimation of equivalent pore radii of pulmonary capillary and alveolar membranes

A. Taylor, Gaar KA · American Journal of Physiology-Legacy Content · 1970 · 281 citations

Natural Sciences, Biophysics, Physiology +15

Deficiency of Alveolar Fluid Glutathione in Patients with Sepsis and the Adult Respiratory Distress Syndrome

Eric R. Pacht, A.P. Timerman, Michael Lykens et al. · CHEST Journal · 1991 · 250 citations

Medicine, Infectious Diseases, Internal Medicine +14

Tight monolayers of rat alveolar epithelial cells: bioelectric properties and active sodium transport

Jeffrey M. Cheek, K. J. Kim, Edward D. Crandall · American Journal of Physiology-Cell Physiology · 1989 · 215 citations

Life Sciences, Cell Biology, Physiology +15

cDNA Cloning and Expression of a Soluble Epoxide Hydrolase from Human Liver

Jeffrey K. Beetham, Tao Tian, Bruce D. Hammock · Archives of Biochemistry and Biophysics · 1993 · 153 citations

Life Sciences, Biochemistry, Molecular Biology +12

Epoxides as products of lipid autoxidation in rat lungs

Alex Sevanian, James F. Mead, Robert A. Stein · Lipids · 1979 · 140 citations

Life Sciences, Biochemistry, Toxicology +17