Concepedia

Thienopyridone Drugs Are Selective Activators of AMP-Activated Protein Kinase β1-Containing Complexes

John W. Scott, Bryce J. W. van Denderen, Sebastian B. Jørgensen, Jane Honeyman, Gregory R. Steinberg, Jonathan S. Oakhill, Tristan J. Iseli, Ann Koay, Paul R. Gooley, David Stapleton,

Chemistry & Biology · 2008 · 250 citations · 36 references

DOI

Concepts

References

36

Role of AMP-activated protein kinase in mechanism of metformin action

Gaochao Zhou, Robert P. Myers, Ying Li et al. · Journal of Clinical Investigation · 2001 · 5.4K citations

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The Anti-diabetic Drugs Rosiglitazone and Metformin Stimulate AMP-activated Protein Kinase through Distinct Signaling Pathways

Lee G.D. Fryer, Asha Parbhu Patel, David Carling · Journal of Biological Chemistry · 2002 · 1K citations · Full text

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Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome

Barbara L. Cool, Bradley A. Zinker, William J. Chiou et al. · Cell Metabolism · 2006 · 918 citations · Full text

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CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations

John W. Scott, Simon A. Hawley, Kevin A. Green et al. · Journal of Clinical Investigation · 2004 · 725 citations · Full text

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Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade

Matthew J. Sanders, Pascal Grondin, Bronwyn D. Hegarty et al. · Biochemical Journal · 2007 · 668 citations · Full text

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