Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation

Simon A. Hawley, Fiona A. Ross, Cyrille Chevtzoff, +8

Cell Metabolism

The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

Simon A. Hawley, Morgan D. Fullerton, Fiona A. Ross, +11

Science

Signal TransductionOxysterolBiochemistryAmp-activated Protein KinaseMedicine +12

CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations

John W. Scott, Simon A. Hawley, Kevin A. Green, +5

Journal of Clinical Investigation

Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction

Kei Sakamoto, Afshan McCarthy, Darrin P. Smith, +4

The EMBO Journal

Muscle FunctionSignal TransductionMolecular PhysiologySkeletal MuscleMuscle Injury +6

Aspirin Inhibits mTOR Signaling, Activates AMP-Activated Protein Kinase, and Induces Autophagy in Colorectal Cancer Cells

Farhat V N Din, Asta Valančiūtė, Vanessa P. Houde, +5

Gastroenterology

Cancer ResearchMitophagyCell AutophagySignal TransductionChemoprevention Strategy +9

A Novel Domain in AMP-Activated Protein Kinase Causes Glycogen Storage Bodies Similar to Those Seen in Hereditary Cardiac Arrhythmias

Emma Hudson, David Pan, John James, +6

Current Biology

Cardiac MuscleCardiomyopathyMolecular PhysiologySignal TransductionHereditary Cardiac Arrhythmias +10

Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase

Jamel Mankouri, Philip R. Tedbury, Sarah N. Gretton, +7

Proceedings of the National Academy of Sciences

Viral ReplicationHepatitis C VirusAmpk ActivityImmunologyMolecular Biology +19

Calmodulin-dependent protein kinase kinase-β activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP

Sarah Fogarty, Simon A. Hawley, Kevin A. Green, +3

Biochemical Journal

Increased Phosphorylation of Skeletal Muscle Glycogen Synthase at NH2-Terminal Sites During Physiological Hyperinsulinemia in Type 2 Diabetes

Kurt Højlund, Peter Stæhr, Bo F. Hansen, +5

Diabetes

5-Aminoimidazole-4-Carboxamide 1-β-<scp>d</scp>-Ribofuranoside Acutely Stimulates Skeletal Muscle 2-Deoxyglucose Uptake in Healthy Men

Daniel J. Cuthbertson, John Babraj, Kirsteen J.W. Mustard, +9

Diabetes

Whole-body Glucose DisposalPharmacotherapyExperimental PharmacologyInsulin SignalingMetabolic Syndrome +20