Concepedia

Novel neutral imidazole-lipophosphoramides for transfection assays

Mathieu Mével, CECILE NEVEU, Cristine Gonçalves, Jean‐Jacques Yaouanc, Chantal Pichon, Paul‐Alain Jaffrès, Patrick Midoux

Chemical Communications · 2008 · 67 citations · 15 references

DOI

Concepts

Abstract

New helper lipids, possessing an imidazole polar head, have been synthesized and included in formulations for transfection assays; these new helper lipids can improve the transfection by a factor of up to 100 compared to the use of DOPE as co-lipid.

References

15

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

Philip L. Felgner, Thomas R. Gadek, Mai Marie Holm et al. · Proceedings of the National Academy of Sciences · 1987 · 5K citations · Full text

, , +15

Use of resonance energy transfer to monitor membrane fusion

Douglas K. Struck, Dick Hoekstra, Richard E. Pagano · Biochemistry · 1981 · 1.3K citations

, , +10

Chloride Accumulation and Swelling in Endosomes Enhances DNA Transfer by Polyamine-DNA Polyplexes

N.D. Sonawane, Francis C. Szoka, A.S. Verkman · Journal of Biological Chemistry · 2003 · 1.1K citations · Full text

, , +14

Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA.

Jean‐Paul Behr, Barbara Demeneix, Jean-Philippe Loeffler et al. · Proceedings of the National Academy of Sciences · 1989 · 720 citations · Full text

, , +16

Cationic Liposomes for Gene Therapy

Andrew D. Miller · Angewandte Chemie International Edition · 1998 · 450 citations

, , +16