Angewandte Chemie International Edition · 2013 · 52 citations · 71 references
PharmacyMedicinal ChemistryCombinatorial ChemistryDrug DesignDrug DiscoveryChemical Library DesignCombinatorial SynthesisDynamic Combinatorial ChemistryLigand BindingReceptor BindingReceptor-ligand InteractionsChemical RecognitionCombinatorial Library ConstructionCombinatorial Library DesignDynamic Combinatorial ReceptorsLigand Design For ReceptorsSmall-molecule Library Design
Making receptors to order: A small dynamic combinatorial library (DCL), formed from two dithiols in water, provides a continuous range of six receptors of different sizes. The majority of the 30 tested amines and ammonium ions amplified receptors from this library, thus spanning the complete receptor-size range and showing that this DCL provides a generic platform for the development of receptors for this important class of compounds. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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Mechanosensitive Self-Replication Driven by Self-Organization
Jacqui M. A. Carnall, Christopher A. Waudby, Ana M. Belenguer et al. · Science · 2010 · 559 citations · Full text