Concepedia

The Neber Route to Substituted Indoles

Douglass F. Taber, Weiwei Tian

Journal of the American Chemical Society · 2006 · 127 citations · 23 references

DOI

Concepts

Abstract

Two complementary procedures have been developed for the conversion of the oximes of alpha-aryl ketones to azirines. On heating, the azirines rearrange smoothly to the corresponding indoles. The overall transformation offers a versatile route to indoles, complementary to the Fischer indole synthesis.

References

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