Deregulated expression of RasGRP1 initiates thymic lymphomagenesis independently of T-cell receptors

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

Yoichi Shinkai · Cell · 1992 · 2.6K citations

Life Sciences, Genetics, Immunology +14

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

Mary Elizabeth Ross, Sheila Shurtleff, W. Kent Williams et al. · Cancer Cell · 2002 · 1.9K citations · Full text

Life Sciences, Bioinformatics, Oncology +16

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

Paweł Kisielow, Horst Blüthmann, Uwe D. Staerz et al. · Nature · 1988 · 1.7K citations

Life Sciences, Cell Biology, Immunology +14

CD5 Expression Is Developmentally Regulated By T Cell Receptor (TCR) Signals and TCR Avidity

Hala S. Azzam, Alex Grinberg, Kin Lui et al. · The Journal of Experimental Medicine · 1998 · 671 citations · Full text

Life Sciences, Cell Biology, Immunology +17

RasGRP is essential for mouse thymocyte differentiation and TCR signaling

Nancy A. Dower, Stacey L. Stang, Drell A. Bottorff et al. · Nature Immunology · 2000 · 408 citations

Life Sciences, Immunology, Molecular Biology +12