Concepedia

New benzimidazole-2-urea derivates as tubulin inhibitors

Wenna Wang, Huimin Cheng, Li Tan, Zhang Zhang, Xiaoxi Zhuang, Huoyou Long, Yang Zhou, Yong Xu, Xiaohong Yang, Ke Ding

Bioorganic & Medicinal Chemistry Letters · 2014 · 45 citations · 20 references

DOI

Concepts

References

20

Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain

Raimond B. G. Ravelli, Benoı̂t Gigant, Patrick A. Curmi et al. · Nature · 2004 · 1.6K citations

, , +14

Structural basis for the regulation of tubulin by vinblastine

Benoı̂t Gigant, Chunguang Wang, Raimond B. G. Ravelli et al. · Nature · 2005 · 730 citations

, , +11

Mode of action of benzimidazoles

Ernest Lacey · Parasitology Today · 1990 · 587 citations

, , +7

Activities of the Microtubule-stabilizing Agents Epothilones A and B with Purified Tubulin and in Cells Resistant to Paclitaxel (Taxol®)

Richard Kowalski, Paraskevi Giannakakou, Ernest Hamel · Journal of Biological Chemistry · 1997 · 512 citations · Full text

, , +8

Discovery of Novel Benzimidazoles as Potent Inhibitors of TIE-2 and VEGFR-2 Tyrosine Kinase Receptors

Masaichi Hasegawa, Naohiko Nishigaki, Yoshiaki Washio et al. · Journal of Medicinal Chemistry · 2007 · 217 citations · Full text

, , +17