Dual inhibition of topoisomerase II and tubulin polymerization by azatoxin, a novel cytotoxic agent

Feasibility of a High-Flux Anticancer Drug Screen Using a Diverse Panel of Cultured Human Tumor Cell Lines

Anne Monks, Dominic A. Scudiero, Philip Skehan et al. · JNCI Journal of the National Cancer Institute · 1991 · 3.3K citations

Medicine, Oncology, Pharmacology +11

Adriamycin-Induced DNA Damage Mediated by Mammalian DNA Topoisomerase II

K M Tewey, Thomas C. Rowe, Liu Yang et al. · Science · 1984 · 1.5K citations

Medicine, Molecular Biology, Pharmacology +17

Display and Analysis of Patterns of Differential Activity of Drugs Against Human Tumor Cell Lines: Development of Mean Graph and COMPARE Algorithm

Kenneth D. Paull, Robert H. Shoemaker, Louis Hodes et al. · JNCI Journal of the National Cancer Institute · 1989 · 969 citations

Medicine, Biostatistics, Oncology +16

Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4'-(9-acridinylamino)methanesulfon-m-anisidide and adriamycin

Leonard A. Zwelling, Stephen Michaels, Leonard C. Erickson et al. · Biochemistry · 1981 · 375 citations

Pharmacy, Cancer Biology, Molecular Biology +15

Protein-linked DNA strand breaks induced in mammalian cells by camptothecin, an inhibitor of topoisomerase I.

Joseph M. Covey, Christine Jaxel, Kurt W. Kohn et al. · PubMed · 1989 · 246 citations

Life Sciences, Cell Biology, Molecular Biology +16