Joseph M. Covey

Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells.

Connie Holm, Joseph M. Covey, Donna Kerrigan et al. · PubMed · 1989 · 370 citations

Molecular Biology, Cell Death, Pharmacotherapy +20

Protein-linked DNA strand breaks induced in mammalian cells by camptothecin, an inhibitor of topoisomerase I.

Joseph M. Covey, Christine Jaxel, Kurt W. Kohn et al. · PubMed · 1989 · 246 citations

Dpc Frequencies, Chromatin, Genome Instability +11

Activated neutrophils induce prolonged DNA damage in neighboring cells

Emily Shacter, E J Beecham, Joseph M. Covey et al. · Carcinogenesis · 1988 · 238 citations

Paraffin Oil-elicited Neutrophils, Dna Damage, Immunology +17

Strategy and planning for chemopreventive drug development: Clinical development plans II

Gary J. Kelloff, James A. Crowell, Ernest T. Hawk et al. · Journal of Cellular Biochemistry · 1996 · 191 citations

Pharmacokinetics, tissue distribution, and metabolism of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (NSC 707545) in CD 2 F 1 mice and Fischer 344 rats

Merrill J. Egorin, Theodore Lagattuta, Deborah R. Hamburger et al. · Cancer Chemotherapy and Pharmacology · 2002 · 175 citations

Pharmacological Study, Biochemistry, Medicine +6