Concepedia

Drug Tolerance in Replicating Mycobacteria Mediated by a Macrophage-Induced Efflux Mechanism

Kristin N. Adams, Kevin K. Takaki, Lynn Connolly, Heather Wiedenhoft, Kathryn Winglee, Olivier Humbert, Paul H. Edelstein, Christine L. Cosma, Lalita Ramakrishnan

Cell · 2011 · 536 citations · 53 references

Open access

Concepts

Life SciencesMicrobiologyPharmacologyAntimicrobial ResistanceInnate ImmunityMedical MicrobiologyAntibacterial ResistanceAntibiotic ResistanceAntibiotic Resistance MechanismsCellular Drug EffluxDrug ToleranceEfflux-mediated ResistanceAntibiotic Efflux ResistanceDrug Efflux MechanismsEfflux Pump-mediated ResistanceIntrinsic Resistance In MycobacteriaMolecular Drug ResistanceMycobacterium Tuberculosis PathogenesisTuberculosis Drug Resistance

References

53

Transcriptional Adaptation of <i>Mycobacterium tuberculosis</i> within Macrophages

Dirk Schnappinger, Sabine Ehrt, Martin I. Voskuil et al. · The Journal of Experimental Medicine · 2003 · 1.4K citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

The Role of the Granuloma in Expansion and Dissemination of Early Tuberculous Infection

J. Muse Davis, Lalita Ramakrishnan · Cell · 2009 · 920 citations · Full text

Medicine, Microbiology, Pathology +12

Cutting Edge: Vitamin D-Mediated Human Antimicrobial Activity against <i>Mycobacterium tuberculosis</i> Is Dependent on the Induction of Cathelicidin

Philip T. Liu, Steffen Stenger, Dominic H. Tang et al. · The Journal of Immunology · 2007 · 767 citations

Life Sciences, Immunology, Microbiology +15

THE PATHOGENESIS OF TUBERCULOSIS

The Medical Journal of Australia · 1952 · 697 citations

Veterinary Medicine, Infectious Diseases, Pathology +13

The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and Humans

David M. Tobin, Jay C. Vary, Gregory S. Walsh et al. · Cell · 2010 · 529 citations · Full text

Life Sciences, Genetics, Microbiology +11