Indazole: a medicinally important heterocyclic moiety

Discovery of 2-{4-[(3<i>S</i>)-Piperidin-3-yl]phenyl}-2<i>H</i>-indazole-7-carboxamide (MK-4827): A Novel Oral Poly(ADP-ribose)polymerase (PARP) Inhibitor Efficacious in BRCA-1 and -2 Mutant Tumors

Philip Jones, Sergio Altamura, Julia K. Boueres et al. · Journal of Medicinal Chemistry · 2009 · 315 citations · Full text

Medicine, Oncology, Pharmacology +16

Development of Dihydropyridone Indazole Amides as Selective Rho-Kinase Inhibitors

Krista Goodman, Haifeng Cui, Sarah E. Dowdell et al. · Journal of Medicinal Chemistry · 2006 · 156 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Treatment with bindarit, a blocker of MCP-1 synthesis, protects mice against acute pancreatitis

Madhav Bhatia, Raina Ramnath, Lakshmi Chevali et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2005 · 141 citations

Medicine, Pathobiology, Pharmacology +17

Synthesis and biological evaluation of N-(7-indazolyl)benzenesulfonamide derivatives as potent cell cycle inhibitors

Latifa Bouissane, Saı̈d El Kazzouli, Stéphane Léonce et al. · Bioorganic & Medicinal Chemistry · 2005 · 129 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Discovery of (3<i>S</i>,3a<i>R</i>)-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2<i>H</i>-benzo[<i>g</i>]indazole-7-carboxylic Acid (PF-3882845), an Orally Efficacious Mineralocorticoid Receptor (MR) Antagonist for Hypertension and Nephropathy

Marvin J. Meyers, Graciela B. Arhancet, Susan L. Hockerman et al. · Journal of Medicinal Chemistry · 2010 · 91 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13