Concepedia

Publication | Open Access

Membrane type 1 matrix metalloproteinase is a crucial promoter of synovial invasion in human rheumatoid arthritis

DOIFull Paper Access

130

Citations

47

References

2009

Year

Mary-Clare Miller, Hugh B. Manning, Abhilash Jain, Linda Troeberg, Jayesh Dudhia, David W. Essex, Ann Sandison, Motoharu Seiki, Jagdeep Nanchahal, Hideaki Nagase,
Arthritis & Rheumatism

Abstract

MT1-MMP serves as an essential collagen-degrading proteinase during pannus invasion in human RA. Specific inhibition of MT1-MMP-dependent invasion may represent a novel therapeutic strategy for RA.

References

YearCitations

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