Adenovirus-mediated human paraoxonase1 gene transfer to provide protection against the toxicity of the organophosphorus pesticide toxicant diazoxon

Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase.

Michael Aviram, Mira Rosenblat, C L Bisgaier et al. · Journal of Clinical Investigation · 1998 · 1.1K citations · Full text

Possible Peroxidative Role, Redox Signaling, Hdl Levels +15

Acute pesticide poisoning: a major global health problem.

J Jeyaratnam · PubMed · 1990 · 761 citations

Pesticide-residue Analysis, Acute Pesticide Poisoning, Biorational Pesticide +16

The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin

Holly Davies, Rebecca J. Richter, Matthew Keifer et al. · Nature Genetics · 1996 · 597 citations

Pharmacology, Toxicology, Medicine +1

Purification of human serum paraoxonase/arylesterase. Evidence for one esterase catalyzing both activities.

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Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma

Bin Li, Meghan Sedlacek, Indumathi Manoharan et al. · Biochemical Pharmacology · 2005 · 526 citations

Biochemistry, Medicine, Natural Sciences +7