Veeraswamy Manne

Discovery of <i>N</i>-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a Selective and Orally Efficacious Inhibitor of the Met Kinase Superfamily

Gretchen M. Schroeder, Yongmi An, Zhen‐Wei Cai et al. · Journal of Medicinal Chemistry · 2009 · 277 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Ha-ras proteins exhibit GTPase activity: point mutations that activate Ha-ras gene products result in decreased GTPase activity.

Veeraswamy Manne, Eva Bekesi, H F Kung · Proceedings of the National Academy of Sciences · 1985 · 195 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Identification and preliminary characterization of protein-cysteine farnesyltransferase.

Veeraswamy Manne, Daniel M. Roberts, Alyson K. Tobin et al. · Proceedings of the National Academy of Sciences · 1990 · 143 citations

Life Sciences, Biochemistry, Molecular Biology +17

Discovery of (<i>R</i>)-7-Cyano-2,3,4,5-tetrahydro-1-(1<i>H</i>-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1<i>H</i>-1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity

John T. Hunt, Charles Z. Ding, Roberta S. Batorsky et al. · Journal of Medicinal Chemistry · 2000 · 134 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors

Mark R. Lackner, Rachel M. Kindt, Pamela M. Carroll et al. · Cancer Cell · 2005 · 132 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +4