Efficacy and safety of immunization with phosphorylated tau against neurofibrillary tangles in mice

Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

Dale Schenk, Robin Barbour, Whitney Dunn et al. · Nature · 1999 · 3.2K citations

Life Sciences, Neurology, Neuroscience +14

Neuropathology of human Alzheimer disease after immunization with amyloid-β peptide: a case report

James A. R. Nicoll, David G. Wilkinson, Clive Holmes et al. · Nature Medicine · 2003 · 1.4K citations

Life Sciences, Neurology, Neuroscience +16

Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

Clive Holmes, Delphine Boche, David Wilkinson et al. · The Lancet · 2008 · 1.4K citations

Life Sciences, Immunology, Neurology +16

Subacute meningoencephalitis in a subset of patients with AD after Aβ42 immunization

J. M. Orgogozo, S. Gilman, Jean‐François Dartigues et al. · Neurology · 2003 · 1.3K citations

Life Sciences, Neurology, Neuroscience +17

Aβ Immunotherapy Leads to Clearance of Early, but Not Late, Hyperphosphorylated Tau Aggregates via the Proteasome

Salvatore Oddo, Lauren M. Billings, J. Patrick Kesslak et al. · Neuron · 2004 · 779 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14