A direct and continuous assay for the determination of thioredoxin reductase activity in cell lysates

Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene.

Vadim N. Gladyshev, Kuan-Teh Jeang, T C Stadtman · Proceedings of the National Academy of Sciences · 1996 · 471 citations

Life Sciences, Biochemistry, Molecular Biology +9

Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells

C. Marzano, Valentina Gandin, Alessandra Folda et al. · Free Radical Biology and Medicine · 2006 · 415 citations

Life Sciences, Oncology, Pharmacology +15

Identification and quantitation of glutathione in hepatic protein mixed disulfides and its relationship to glutathione disulfide

Regina Brigelius, Christian Muckel, Theodorus P.M. Akerboom et al. · Biochemical Pharmacology · 1983 · 349 citations

Life Sciences, Biochemistry, Protein Biochemistry +6

Thioredoxin, a Redox Enzyme Released in Infection and Inflammation, Is a Unique Chemoattractant for Neutrophils, Monocytes, and T Cells

Riccardo Bertini, O. M. Zack Howard, Huifang Dong et al. · The Journal of Experimental Medicine · 1999 · 339 citations · Full text

Life Sciences, Immunology, Pharmacology +13

Preparation and assay of mammalian thioredoxin and thioredoxin reductase

Elias S.J. Arnér, Liangwei Zhong, Arne Holmgren · Methods in enzymology on CD-ROM/Methods in enzymology · 1999 · 320 citations

Life Sciences, Biochemistry, Molecular Genetics +10