Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells

C. Marzano, Valentina Gandin, Alessandra Folda, +3

Free Radical Biology and Medicine

Reductive StressAuranofin Induces ApoptosisMedicineApoptosisCell Death +8

Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase

Valentina Gandin, Aristi P. Fernandes, Maria Pia Rigobello, +8

Biochemical Pharmacology

BiochemistryCancer Cell DeathMedicineApoptosisCell Death +8

Pt(<scp>iv</scp>) derivatives of cisplatin and oxaliplatin with phenylbutyrate axial ligands are potent cytotoxic agents that act by several mechanisms of action

Raji Raveendran, Jeremy Phillip Braude, Ezequiel Wexselblatt, +5

Chemical Science

A novel copper complex induces paraptosis in colon cancer cells <i>via</i> the activation of ER stress signalling

Valentina Gandin, Maura Pellei, Francesco Tisato, +3

Journal of Cellular and Molecular Medicine

ApoptosisPathologyCell DeathEr StressCancer Biology +17

Triple action Pt(<scp>iv</scp>) derivatives of cisplatin: a new class of potent anticancer agents that overcome resistance

Emanuele Petruzzella, Roman Sirota, Irene Solazzo, +2

Chemical Science

In Vitro Antitumor Activity of the Water Soluble Copper(I) Complexes Bearing the Tris(hydroxymethyl)phosphine Ligand

Cristina Marzano, Valentina Gandin, Maura Pellei, +7

Journal of Medicinal Chemistry

ChemistryInorganic CompoundMedicinal ChemistryPhosphine LigandWater Soluble Copper +18

In vitro and in vivo anticancer activity of tridentate thiosemicarbazone copper complexes: Unravelling an unexplored pharmacological target

Mauro Carcelli, Matteo Tegoni, Jennifer Bartoli, +5

European Journal of Medicinal Chemistry

Medicinal ChemistryVivo Anticancer ActivityUnexplored Pharmacological TargetMedicineBioactive Metal +5

Synthesis, Characterization, and in Vitro Antitumor Properties of Tris(hydroxymethyl)phosphine Copper(I) Complexes Containing the New Bis(1,2,4-triazol-1-yl)acetate Ligand

Cristina Marzano, Maura Pellei, Davide Colavito, +5

Journal of Medicinal Chemistry

Selenium induces a multi‐targeted cell death process in addition to <scp>ROS</scp> formation

Marita Wallenberg, Sougat Misra, Agata M. Wasik, +4

Journal of Cellular and Molecular Medicine

ApoptosisCell DeathCell Death MechanismsRedox BiologyTumor Biology +18

A Quadruple‐Action Platinum(IV) Prodrug with Anticancer Activity Against KRAS Mutated Cancer Cell Lines

Emanuele Petruzzella, Jeremy Phillip Braude, Janice R. Aldrich‐Wright, +2

Angewandte Chemie International Edition