RAD51 Haploinsufficiency Causes Congenital Mirror Movements in Humans

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice.

Teruhisa Tsuzuki, Youichi Fujii, Kunihiko Sakumi et al. · Proceedings of the National Academy of Sciences · 1996 · 790 citations · Full text

Embryonic Mice, Rad51 Null Mutation, Gene Therapies +13

Insights into DNA recombination from the structure of a RAD51–BRCA2 complex

Luca Pellegrini, David S. Yu, Thomas Lo et al. · Nature · 2002 · 694 citations

Chromatin, Genome Instability, Genetics +9

Purified human BRCA2 stimulates RAD51-mediated recombination

Ryan B. Jensen, Aura Carreira, Stephen C. Kowalczykowski · Nature · 2010 · 690 citations

Genome Instability, Genetics, Genetic Mechanism +4

A Mutation in Mouse <i>rad51</i> Results in an Early Embryonic Lethal That Is Suppressed by a Mutation in <i>p53</i>

Dae‐Sik Lim, Paul Hasty · Molecular and Cellular Biology · 1996 · 687 citations · Full text

Genome Instability, Developmental Biology, Cell Division +13

BCR/ABL Regulates Mammalian RecA Homologs, Resulting in Drug Resistance

Artur Słupianek, Christoph Schmütte, Gregory Tombline et al. · Molecular Cell · 2001 · 309 citations · Full text

Molecular Pharmacology, Signal Transduction, Molecular Regulation +3