Kunihiko Sakumi

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice.

Teruhisa Tsuzuki, Youichi Fujii, Kunihiko Sakumi et al. · Proceedings of the National Academy of Sciences · 1996 · 790 citations · Full text

Embryonic Mice, Rad51 Null Mutation, Gene Therapies +13

Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis.

Kunihiko Sakumi, Masato Furuichi, Teruhisa Tsuzuki et al. · Journal of Biological Chemistry · 1993 · 439 citations · Full text

Genetics, Molecular Biology, Molecular Genetics +19

Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption.

Kunihiko Sakumi, Yohei Tominaga, Masato Furuichi et al. · PubMed · 2003 · 235 citations

Oncogenic Agent, Medicine, Mth1 Gene Disruption +12

Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs

Sugako Oka, Mizuki Ohno, Daisuke Tsuchimoto et al. · The EMBO Journal · 2008 · 215 citations · Full text

Chromatin, Dna Damage, Mitochondrial Dnas +11

Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease

Kyota Fujita, Toshihiro Seike, Noriko Yutsudo et al. · PLoS ONE · 2009 · 198 citations · Full text

Lipid Peroxidation, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model, Redox Biology +17