An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

Jürgen M. Lehmann, Linda B. Moore, Tracey Smith-Oliver, +3

Journal of Biological Chemistry

Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

Peter Tontonoz, Erding Hu, Bruce M. Spiegelman

Cell

Transcriptional RegulationCell SignalingPhysiologyAdipose TissueMetabolic Regulation +8

Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)

Masanobu Oshima, Joseph Dinchuk, Stacia Kargman, +6

Cell

InflammationIntestinal PolyposisMedicineGastroenterologyCell Death +7

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

Steven A. Kliewer, Scott S. Sundseth, Stacey A. Jones, +8

Proceedings of the National Academy of Sciences

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ

Barry M. Forman, Jasmine Chen, Ronald M. Evans

Proceedings of the National Academy of Sciences

Metabolic SyndromeHealth SciencesBiochemistryFatty AcidsMedicine +12

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation

Steven A. Kliewer, James M. Lenhard, Timothy M. Willson, +3

Cell

Metabolic SyndromeProstaglandin J2 MetaboliteAdipokinesBiochemistryMedicine +7

PPARγ Promotes Monocyte/Macrophage Differentiation and Uptake of Oxidized LDL

Peter Tontonoz, László Nagy, Jacqueline G. Alvarez, +2

Cell

InflammationOxysterolLipid PeroxidationImmunologyOxidized Ldl +6

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors.

Steven A. Kliewer, Barry M. Forman, Bruce Blumberg, +5

Proceedings of the National Academy of Sciences

Lipid PeroxidationSignaling PathwayCell SignalingReceptor (Biochemistry)Reactive Oxygen Specie +14

Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors

Christine Dreyer, Grigorios Krey, H. J. Keller, +3

Cell

OxysterolBiochemistryMedicineHormonal ReceptorPhysiology +7

Expression of cyclooxygenase-1 and -2 in human colorectal cancer.

Hajime Sano, Yutaka Kawahito, Ronald L. Wilder, +7

PubMed

InflammationTumor BiologyAnti-inflammatoryOncologyCox-2 Polypeptides +13