Normal and Reversed Supramolecular Chirality of Insulin Fibrils Probed by Vibrational Circular Dichroism at the Protofilament Level of Fibril Structure

Self-Propagating, Molecular-Level Polymorphism in Alzheimer's ß-Amyloid Fibrils

Aneta T. Petkova, Richard D. Leapman, Zhihong Guo et al. · Science · 2005 · 1.7K citations

Neurodegenerative Diseases, Alzheimer's Disease, Electron Microscopy +13

Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells.

Per Westermark, Christer Wernstedt, Erik Wilander et al. · Proceedings of the National Academy of Sciences · 1987 · 975 citations · Full text

Biochemistry, Diabetic Cat, Human Insulinoma Iapp +14

Applied Smoothing Techniques for Data Analysis

Richard D. DeVeaux, Adrian Bowman, Adelchi Azzalini · Technometrics · 1999 · 946 citations

Data Analysis, Applied Smoothing Techniques, Engineering +10

The protofilament structure of insulin amyloid fibrils

José L. Jiménez, Ewan J. Nettleton, Mario Bouchard et al. · Proceedings of the National Academy of Sciences · 2002 · 832 citations · Full text

Dependence of α-Synuclein Aggregate Morphology on Solution Conditions

Wolfgang Hoyer, Thomas Antony, Dmitry Cherny et al. · Journal of Molecular Biology · 2002 · 568 citations · Full text

Neurodegenerative Diseases, α-Synuclein Aggregate Morphology, Protein Misfolding +3