Covalent alkylation of dna with duocarmycin A. Identification of abasic site structure

Isolation and Structure of a Covalent Cross-Link Adduct Between Mitomycin C and DNA

Maria Tomasz, Roselyn Lipman, Dondapati Chowdary et al. · Science · 1987 · 455 citations

Pharmacy, Cancer Biology, Molecular Biology +15

Reaction of the Antitumor Antibiotic CC-1065 with DNA: Structure of a DNA Adduct with DNA Sequence Specificity

Laurence H. Hurley, Vincent L. Reynolds, David H. Swenson et al. · Science · 1984 · 204 citations

Life Sciences, Molecular Biology, Pharmacology +17

Duocarmycin A, a new antitumor antibiotic from Streptomyces.

ISAMI TAKAHASHI, Keiichi Takahashi, Michio Ichimura et al. · The Journal of Antibiotics · 1988 · 195 citations · Full text

Medicine, Microbiology, Chemotherapy +4

Synthesis and preliminary evaluation of agents incorporating the pharmacophore of the duocarmycin/pyrindamycin alkylation subunit: identification of the CC-1065/duocarmycin common pharmacophore

Dale L. Boger, Takayoshi Ishizaki, Hamideh Zarrinmayeh et al. · The Journal of Organic Chemistry · 1990 · 93 citations

Medicine, Medicinal Chemistry, Pharmacology +7

Application of 2-cyanoethyl N,N,N′,N′-tetraisopropylphosphorodiamidite for<i>in situ</i>preparation of deoxyribonucleoside phosphoramidites and their use in polymer-supported synthesis of oligodeoxyribonucleotides

John Nielsen, Michael Taagaard, J. E. MARUGG et al. · Nucleic Acids Research · 1986 · 86 citations · Full text

Pharmacy, Biotechnology, Molecular Biology +14