Concepedia

Abasic Sites

Abasic Sites is a type of DNA lesion characterized by the absence of a nitrogenous base in the sugar-phosphate backbone, resulting from the hydrolysis or enzymatic removal of a purine or pyrimidine base, which disrupts normal base pairing and necessitates repair through the base excision repair pathway.

686

Publications

42K

Citations

2.1K

Authors

564

Institutions

Publications per year

2017–2026

108

Variants

Ap SitesApurinic/apyrimidinic Sites

Parents

Publications

686

8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity.

Julia Tchou, Hiroshi Kasai, Shinya Shibutani et al. · Proceedings of the National Academy of Sciences · 1991 · 679 citations

, , +13

Two Pathways for Base Excision Repair in Mammalian Cells

Guido Fròsina, Paola Fortini, Ottavio Rossi et al. · Journal of Biological Chemistry · 1996 · 531 citations · Full text

, , +14

Removal of deaminated cytosines and detection of in vivo methylation in ancient DNA

Adrian W. Briggs, Udo Stenzel, Matthias Meyer et al. · Nucleic Acids Research · 2009 · 523 citations · Full text

, , +16

Base Excision Repair Is Impaired in Mammalian Cells Lacking Poly(ADP-ribose) Polymerase-1

Françoise Dantzer, Guadelupe de la Rubia, Josiane Ménissier‐de Murcia et al. · Biochemistry · 2000 · 497 citations

, , +17

Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation

Betsy M. Sutherland, Paula V. Bennett, Olga Sidorkina et al. · Proceedings of the National Academy of Sciences · 2000 · 468 citations

, , +17

1–5 of 686

Authors

2.1K

  1. MM
    Marc M. Greenberg

    Johns Hopkins University, United States

    21 publications · 961 citations

    16

    h-index

  2. LP
    Louise Prakash

    The University of Texas Medical Branch at Galveston, United States

    14 publications · 1.9K citations

    14

    h-index

  3. SP
    Satya Prakash

    The University of Texas Medical Branch at Galveston, United States

    14 publications · 1.9K citations

    14

    h-index

  4. KS
    Kent S. Gates

    University of Missouri, United States

    14 publications · 670 citations

    13

    h-index

  5. DM
    David M. Wilson

    National Institute on Aging, United States

    13 publications · 978 citations

    13

    h-index

1–5 of 2.1K

Institutions

564

  1. Centre National de la Recherche Scientifique

    Paris, France

    28 h-index

    204 publications

    12.5K citations

  2. National Institutes of Health

    Bethesda, United States

    21 h-index

    89 publications

    9K citations

  3. The University of Texas Medical Branch at Galveston

    Galveston, United States

    20 h-index

    79 publications

    10.1K citations

  4. State University of New York

    Albany, United States

    18 h-index

    63 publications

    8.2K citations

  5. Stony Brook University

    Stony Brook, United States

    17 h-index

    58 publications

    7.7K citations

  6. Johns Hopkins University

    Baltimore, United States

    16 h-index

    69 publications

    3.1K citations

  7. National Institute of Environmental Health Sciences

    Durham, United States

    15 h-index

    42 publications

    5.8K citations

  8. Emory University

    Atlanta, United States

    15 h-index

    40 publications

    2.7K citations

1–8 of 564

Venues

  1. Nucleic Acids Research

    112 publications · 6.7K citations

    47

    h-index

  2. Journal of Biological Chemistry

    JBC · 59 publications · 6.1K citations

    42

    h-index

  3. Biochemistry

    83 publications · 4.9K citations

    41

    h-index

  4. Journal of the American Chemical Society

    JACS · 32 publications · 2.5K citations

    27

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 31 publications · 4.1K citations

    25

    h-index

1–5