Polymorphisms in the CBS Gene Associated with Decreased Risk of Coronary Artery Disease and Increased Responsiveness to Total Homocysteine Lowering by Folic Acid

A Second Common Mutation in the Methylenetetrahydrofolate Reductase Gene: An Additional Risk Factor for Neural-Tube Defects?

N.M.J. van der Put, F. Gabreëls, E M Stevens et al. · The American Journal of Human Genetics · 1998 · 1.6K citations · Full text

Developmental Biology, Second Common Mutation, Neural-tube Defects +12

Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomised trials

BMJ · 1998 · 1.1K citations · Full text

Nutrition, Blood Homocysteine, Nutrient Bioavailability +17

Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine.

Gordon Starkebaum, John M. Harlan · Journal of Clinical Investigation · 1986 · 818 citations · Full text

Endothelial Cells, Homocysteine Oxidation, Toxic Effects +18

Vascular dysfunction in monkeys with diet-induced hyperhomocyst(e)inemia.

Steven R. Lentz, Christopher G. Sobey, D J Piegors et al. · Journal of Clinical Investigation · 1996 · 503 citations · Full text

Animal Physiology, Nutrition, Metabolic Disorder +13

Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders

Daniel Leclerc · Human Molecular Genetics · 1996 · 398 citations

Mendelian Disorder, Biochemistry, Genetic Disorder +13