Concepedia

Aberrant Splicing Caused by Single Nucleotide Polymorphism c.516G>T [Q172H], a Marker of CYP2B6*6, Is Responsible for Decreased Expression and Activity of CYP2B6 in Liver

Marco H. Hofmann, Julia Blievernicht, Kathrin Klein, Elke Schaeffeler, Matthias Schwab, Ulrich M. Zanger

Journal of Pharmacology and Experimental Therapeutics · 2008 · 213 citations · 30 references

DOI

Concepts

References

30

A New Statistical Method for Haplotype Reconstruction from Population Data

Matthew Stephens, Nicholas Smith, Peter Donnelly · The American Journal of Human Genetics · 2001 · 7.5K citations · Full text

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Two-sided confidence intervals for the single proportion: comparison of seven methods

Robert G. Newcombe · Statistics in Medicine · 1998 · 5.1K citations

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A Comparison of Bayesian Methods for Haplotype Reconstruction from Population Genotype Data

Matthew Stephens, Peter Donnelly · The American Journal of Human Genetics · 2003 · 3.5K citations · Full text

, , +13

The Cytochrome P450 2B6 (CYP2B6) Is the Main Catalyst of Efavirenz Primary and Secondary Metabolism: Implication for HIV/AIDS Therapy and Utility of Efavirenz as a Substrate Marker of CYP2B6 Catalytic Activity

Bryan A. Ward, J. Christopher Gorski, David R. Jones et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 594 citations

, , +17

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver.

Thomas Lang, Kathrin Klein, Joachim E. Fischer et al. · Pharmacogenetics · 2001 · 569 citations

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