Evi1 defines leukemia-initiating capacity and tyrosine kinase inhibitor resistance in chronic myeloid leukemia

Imatinib Compared with Interferon and Low-Dose Cytarabine for Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia

Stephen G. O’Brien, François Guilhot, Richard A. Larson et al. · New England Journal of Medicine · 2003 · 3.6K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +10

Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome

Brian Druker, Charles L. Sawyers, Hagop M. Kantarjian et al. · New England Journal of Medicine · 2001 · 2.7K citations · Full text

Medicine, Hematology, Oncology +17

Prognostically Useful Gene-Expression Profiles in Acute Myeloid Leukemia

Peter J.M. Valk, Roel G.W. Verhaak, M. Antoinette Beijen et al. · New England Journal of Medicine · 2004 · 1.4K citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro

Susan M. Graham, Heather G. Jørgensen, Elaine Allan et al. · Blood · 2002 · 1.2K citations · Full text

Life Sciences, Cell Biology, Hematology +13

Stem cell gene expression programs influence clinical outcome in human leukemia

Kolja Eppert, Katsuto Takenaka, Eric R. Lechman et al. · Nature Medicine · 2011 · 1K citations

Medicine, Cancer Biology, Oncology +16