Publication | Closed Access
SYNTHESIS, RESOLUTION AND CHARGE‐DONOR PROPERTIES OF SIX TRYPTOPHAN ANALOGUES
19
Citations
20
References
1979
Year
Medicinal ChemistryBioorganic ChemistryPeptide HormonesBiochemistryNatural SciencesPeptide LibraryCharge-transfer PropertiesPeptide SynthesisOrganic ChemistryChemistryTryptophan AnaloguesNon-peptide LigandPharmacologySynthetic ChemistryNeuropeptides
In order to investigate the special function of tryptophan in peptide hormones, six tryptophan analogues have been synthesized, in which structural resemblance has been grossly retained and potentially essential properties have only partially been varied. The L-enantiomers have been isolated after enzymatic digestion of racemic dipeptide derivatives, and charge-transfer properties of the compounds have been studied.
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