Amyloid-β precursor protein mediates neuronal toxicity of amyloid β through Go protein activation

Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis

Rakez Kayed, Elizabeth Head, Jennifer L. Thompson et al. · Science · 2003 · 4.1K citations

Life Sciences, Biochemistry, Neuroscience +17

Diffusible, nonfibrillar ligands derived from Aβ _1–42 are potent central nervous system neurotoxins

Mary P. Lambert, Avlin Barlow, Brett A. Chromy et al. · Proceedings of the National Academy of Sciences · 1998 · 3.5K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

Montserrat Arrasate, Siddhartha Mitra, Erik S. Schweitzer et al. · Nature · 2004 · 2K citations

Life Sciences, Neurobiology, Neuroscience +15

RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease

Shi Du Yan, Xi Chen, Jin Fu et al. · Nature · 1996 · 2K citations

Life Sciences, Neurobiology, Neuroscience +12

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

Alfredo Lorenzo, Bruce A. Yankner · Proceedings of the National Academy of Sciences · 1994 · 1.3K citations

Life Sciences, Neurobiology, Neuroscience +17