Concepedia

Design, synthesis and biological evaluation of a novel class of potent TGR5 agonists based on a 4-phenyl pyridine scaffold

Junjie Zhu, Mengmeng Ning, Cen Guo, Lina Zhang, Guoyu Pan, Ying Leng, Jianhua Shen

European Journal of Medicinal Chemistry · 2013 · 14 citations · 21 references

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References

21

Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes

Kitt Falk Petersen, Sylvie Dufour, Douglas E. Befroy et al. · New England Journal of Medicine · 2004 · 2.2K citations · Full text

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Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

Mitsuhiro Watanabe, Sander M. Houten, Chikage Mataki et al. · Nature · 2006 · 2.2K citations · Full text

, , +14

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

Charles Thomas, Antimo Gioiello, Lilia G. Noriega et al. · Cell Metabolism · 2009 · 1.8K citations · Full text

, , +10

A G Protein-coupled Receptor Responsive to Bile Acids

Yuji Kawamata, Ryo Fujii, Masaki Hosoya et al. · Journal of Biological Chemistry · 2003 · 1.6K citations · Full text

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Identification of membrane-type receptor for bile acids (M-BAR)

Takaharu Maruyama, Yasuhisa Miyamoto, Takao Nakamura et al. · Biochemical and Biophysical Research Communications · 2002 · 975 citations

, , +14