Sir2 histone deacetylase prevents programmed cell death caused by sustained activation of the Hog1 stress‐activated protein kinase

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

Konrad T. Howitz, Kevin J. Bitterman, Haim Cohen et al. · Nature · 2003 · 3.7K citations

Lifespan Extension, Natural Sciences, Molecular Biology +5

Extrachromosomal rDNA Circles— A Cause of Aging in Yeast

David Sinclair, Leonard Guarente · Cell · 1997 · 1.5K citations · Full text

Chromatin, Genome Instability, Chromosome Dynamics +10

Remodeling of Yeast Genome Expression in Response to Environmental Changes

Helen C. Causton, Bing Ren, Sang Seok Koh et al. · Molecular Biology of the Cell · 2001 · 1.4K citations

A two-component system that regulates an osmosensing MAP kinase cascade in yeast

Tatsuya Maeda, Susannah M. Wurgler‐Murphy, Haruo Saito · Nature · 1994 · 1.1K citations

Signal Transduction, Map Kinase Cascade, Natural Sciences +12

Oxygen Stress: A Regulator of Apoptosis in Yeast

Frank Madeo, Eleonore Fröhlich, Martin Ligr et al. · The Journal of Cell Biology · 1999 · 1K citations · Full text

Reductive Stress, Oxygen Stress, Biochemistry +14