Time-resolved Absorption and UV Resonance Raman Spectra Reveal Stepwise Formation of T Quaternary Contacts in the Allosteric Pathway of Hemoglobin

Haemoglobin: The structural changes related to ligand binding and its allosteric mechanism

J.M. Baldwin, Cyrus Chothia · Journal of Molecular Biology · 1979 · 865 citations

Biochemistry, Protein Folding, Natural Sciences +6

Watching a Protein as it Functions with 150-ps Time-Resolved X-ray Crystallography

Friedrich Schotte, Manho Lim, Timothy A. Jackson et al. · Science · 2003 · 747 citations

X-ray Crystallography, Protein Assembly, Molecular Biology +18

Two-State Allosteric Behavior in a Single-Domain Signaling Protein

Brian F. Volkman, Doron Lipson, David E. Wemmer et al. · Science · 2001 · 592 citations

Biophysical Modeling, Protein Assembly, Molecular Biology +19

Assignment of Protoheme Resonance Raman Spectrum by Heme Labeling in Myoglobin

Songzhou Hu, Kevin M. Smith, Thomas G. Spiro · Journal of the American Chemical Society · 1996 · 474 citations

Spectroscopic Method, Resonance Raman, Molecular Spectroscopy +11

Targeted Molecular Dynamics Simulation of Conformational Change-Application to the T ↔ R Transition in Insulin

J. Schlitter, Michael Engels, Péter Krüger et al. · Molecular Simulation · 1993 · 425 citations

Biophysical Modeling, Conformational Change-application, Engineering +20