Concepedia

Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals

Joanne E. Hesse, Michael R. Lieber, Martin Gellert, Kiyoshi Mizuuchi

Cell · 1987 · 345 citations · 34 references

Concepts

Life SciencesGeneticsMolecular BiologyCytogeneticsImmunogeneticsB Cell BiologyB Cell DevelopmentImmunoglobulin Gene RearrangementLymphocyte DevelopmentRecombination IntermediatesV(d)j RecombinationImmunoglobulin Gene RecombinationImmunoglobulin Heavy Chain RearrangementImmunoglobulin Light Chain RearrangementPre-b Cell StageV(d)j Recombination MachineryV(d)j Recombination MechanismV(d)j Recombination Regulation

References

34

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

H.C. Birnboim, Janine Doly · Nucleic Acids Research · 1979 · 14.9K citations · Full text

Life Sciences, Genetics, Molecular Biology +11

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

Allan M. Maxam, Walter Gilbert · Methods in enzymology on CD-ROM/Methods in enzymology · 1980 · 14.7K citations

Pharmacy, Biotechnology, Molecular Biology +13

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

Jeffrey Vieira, Joachim Messing · Gene · 1982 · 6.1K citations

Life Sciences, Genetics, Molecular Biology +15

Somatic generation of antibody diversity

Susumu Tonegawa · Nature · 1983 · 4K citations

Life Sciences, Biotechnology, Immunology +14

Somatic generation of antibody diversity.

PubMed · 1976 · 3.3K citations

Life Sciences, Biotechnology, Immunology +14