PLoS ONE · 2013 · 24 citations · 21 references
Life SciencesGeneticsMolecular GeneticsCytogeneticsGenomicsReproductive GeneticsAnimal GenomicsSex-linked InheritanceSpermatogenesis GeneticsIntersex DisordersIntersex PhenotypesMaster Sex-determining GenesReal-time Polymerase Chain Reaction (Pcr)Sex Chromosome DuplicationsSex Determination GenesSex Determination GenomicsWhole-genome Sequencing Analysis
A complex network of genes determines sex in mammals. Here, we studied a European roe deer with an intersex phenotype that was consistent with a XY genotype with incomplete male-determination. Whole genome sequencing and quantitative real-time PCR analyses revealed a triple dose of the SOX9 gene, allowing insights into a new genetic defect in a wild animal.
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De novo assembly of human genomes with massively parallel short read sequencing
Ruiqiang Li, Hongmei Zhu, Jue Ruan et al. · Genome Research · 2009 · 3K citations · Full text
Expression of a candidate sex-determining gene during mouse testis differentiation
Peter Koopman, Andrea Münsterberg, Blanche Capel et al. · Nature · 1990 · 850 citations