Regioselective Rhodium(II)‐Catalyzed Hydroaminations of Propargylguanidines

Abstract

Different than others: Dimeric rhodium(II) carboxylates uniquely catalyze the 6-endo-dig selective hydroamination of propargylguanidines while tranditional π-Lewis acids are typically 5-exo-dig selective (see scheme, oct=octanoate). Furthermore, this represents a new role for RhII to activate alkynes for addition chemistry. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.