Organocatalytic Synthesis of Spiro[pyrrolidin-3,3′-oxindoles] with High Enantiopurity and Structural Diversity

Xiaohua Chen, Qiang Wei, Shi‐Wei Luo, +2

Journal of the American Chemical Society

Precision glycocalyx editing as a strategy for cancer immunotherapy

Han Xiao, Elliot C. Woods, Petar Vukojicic, +1

Proceedings of the National Academy of Sciences

Consecutive Intramolecular Hydroamination/Asymmetric Transfer Hydrogenation under Relay Catalysis of an Achiral Gold Complex/Chiral Brønsted Acid Binary System

Zhi‐Yong Han, Han Xiao, Xiaohua Chen, +1

Journal of the American Chemical Society

Chemical EngineeringEngineeringDirect TransformationRelay CatalysisOrganic Chemistry +11

Targeted glycan degradation potentiates the anticancer immune response in vivo

Melissa A. Gray, Michal A. Stanczak, Natália Rodrigues Mantuano, +10

Nature Chemical Biology

Cancer ImmunosurveillanceImmunologyImmune Checkpoint InhibitorGlycan DegradationTumor Targeting +5

Bispecific CAR-T cells targeting both CD19 and CD22 for therapy of adults with relapsed or refractory B cell acute lymphoblastic leukemia

Hanren Dai, Zhiqiang Wu, Hejin Jia, +11

Journal of Hematology & Oncology

A Versatile Platform for Single- and Multiple-Unnatural Amino Acid Mutagenesis in <i>Escherichia coli</i>

Abhishek Chatterjee, Sophie Sun, Jennifer L. Furman, +2

Biochemistry

EngineeringUnnatural Amino AcidMolecular BiologyEscherichia ColiProtein Synthesis +15

Optimized tandem CD19/CD20 CAR-engineered T cells in refractory/relapsed B cell lymphoma

Chuan Tong, Yang Liu, Xingyu Ji, +11

Blood

Low-dose decitabine priming endows CAR T cells with enhanced and persistent antitumour potential via epigenetic reprogramming

Yao Wang, Chuan Tong, Hanren Dai, +12

Nature Communications

Genetic Incorporation of Multiple Unnatural Amino Acids into Proteins in Mammalian Cells

Han Xiao, Abhishek Chatterjee, Seihyun Choi, +3

Angewandte Chemie International Edition

Unnatural Amino AcidImmunologyMolecular BiologyProtein GeneticsProtein Synthesis +19

Randomized, Controlled Trial of Acupuncture for the Treatment of Hot Flashes in Breast Cancer Patients

Gary Deng, Andrew J. Vickers, K. Simon Yeung, +8

Journal of Clinical Oncology