Concepedia

Hydrophobically modified glycol chitosan nanoparticles-encapsulated camptothecin enhance the drug stability and tumor targeting in cancer therapy

Kyung Hyun Min, Kyeongsoon Park, Yoo-Shin Kim, Sang Mun Bae, Seulki Lee, Hyung Gon Jo, Rang‐Woon Park, In-San Kim, Seo Young Jeong, Kwangmeyung Kim,

Journal of Controlled Release · 2008 · 462 citations · 34 references

DOI

Concepts

References

34

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

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Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment

Susan K. Hobbs, Wayne L. Monsky, Fan Yuan et al. · Proceedings of the National Academy of Sciences · 1998 · 2.4K citations

, , +17

Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata<sup>1,2</sup>

Monroe E. Wall, Mansukh C. Wani, Clarence Cook et al. · Journal of the American Chemical Society · 1966 · 2.2K citations

, , +8

Openings between Defective Endothelial Cells Explain Tumor Vessel Leakiness

Hiroya Hashizume, Shunichi Morikawa, John W. McLean et al. · American Journal Of Pathology · 2000 · 1.7K citations · Full text

, , +10

Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin.

Yaw Huei Hsiang, Leroy F. Liu · PubMed · 1988 · 844 citations

, , +12