Expression patterns of transcription factors in progressively transformed germinal centers and Hodgkin lymphoma

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

Stephen L. Nutt, Barry Heavey, Antonius Rolink et al. · Nature · 1999 · 1.2K citations

Life Sciences, Cell Biology, Molecular Biology +14

A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes

Harinder Singh, Ranjan Sen, David Baltimore et al. · Nature · 1986 · 1.2K citations

Life Sciences, Genetics, Molecular Biology +17

Expression of a large family of POU-domain regulatory genes in mammalian brain development

Xi He, Maurice N. Treacy, Donna M. Simmons et al. · Nature · 1989 · 845 citations

Life Sciences, Developmental Biology, Genetics +16

Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.

Holger Kanzler, Ralf Küppers, Martin‐Leo Hansmann et al. · The Journal of Experimental Medicine · 1996 · 757 citations · Full text

Veterinary Medicine, Oncology, Pathology +17

A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes

Louis M. Staudt, Harinder Singh, Ranjan Sen et al. · Nature · 1986 · 710 citations

Life Sciences, Immunology, Molecular Biology +12