Concepedia

Identification of cysteinylation of a free cysteine in the Fab region of a recombinant monoclonal IgG1 antibody using Lys-C limited proteolysis coupled with LC/MS analysis

Himanshu S. Gadgil, Pavel V. Bondarenko, Gary D. Pipes, Thomas M. Dillon, Douglas D. Banks, Jeffrey Abel, Gerd R. Kleemann, Michael J. Treuheit

Analytical Biochemistry · 2006 · 115 citations · 28 references

DOI

Concepts

References

28

A simple method for displaying the hydropathic character of a protein

Jack Kyte, Russell F. Doolittle · Journal of Molecular Biology · 1982 · 23.1K citations

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Crystal Structure of a Neutralizing Human IgG Against HIV-1: A Template for Vaccine Design

Erica Ollmann Saphire, Paul W.H.I. Parren, Ralph Pantophlet et al. · Science · 2001 · 932 citations

, , +17

THE COVALENT STRUCTURE OF AN ENTIRE γG IMMUNOGLOBULIN MOLECULE

Gerald M. Edelman, Bruce A. Cunningham, W. Einar Gall et al. · Proceedings of the National Academy of Sciences · 1969 · 895 citations · Full text

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Structural Analysis of Human IgG-Fc Glycoforms Reveals a Correlation Between Glycosylation and Structural Integrity

S. Krapp, Yusuke Mimura, Roy Jefferis et al. · Journal of Molecular Biology · 2003 · 664 citations

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The influence of glycosylation on the thermal stability and effector function expression of human IgG1-Fc: properties of a series of truncated glycoforms

Yusuke Mimura, S. Church, Rodolfo Ghirlando et al. · Molecular Immunology · 2000 · 329 citations

, , +15