Himanshu S. Gadgil

Succinimide formation at Asn 55 in the complementarity determining region of a recombinant monoclonal antibody IgG1 heavy chain

Boxu Yan, Sean Steen, David M. Hambly et al. · Journal of Pharmaceutical Sciences · 2009 · 168 citations

Succinimide Formation, Asn 55, Immunocytochemical Technique +12

Elucidation of Acid-induced Unfolding and Aggregation of Human Immunoglobulin IgG1 and IgG2 Fc

Ramil F. Latypov, Sabine Hogan, Hollis Lau et al. · Journal of Biological Chemistry · 2011 · 147 citations · Full text

Immunocytochemical Technique, Protein Assembly, Immunology +22

Identification of cysteinylation of a free cysteine in the Fab region of a recombinant monoclonal IgG1 antibody using Lys-C limited proteolysis coupled with LC/MS analysis

Himanshu S. Gadgil, Pavel V. Bondarenko, Gary D. Pipes et al. · Analytical Biochemistry · 2006 · 115 citations

Autoimmune Disease, Biochemistry, Free Cysteine +14

Effect of Sugar Molecules on the Viscosity of High Concentration Monoclonal Antibody Solutions

Feng He, Christopher Woods, Jennifer R. Litowski et al. · Pharmaceutical Research · 2011 · 111 citations

Bioanalysis, Sugar Molecules, Immunochemistry +6

The LC/MS Analysis of Glycation of IGG Molecules in Sucrose Containing Formulations

Himanshu S. Gadgil, Pavel V. Bondarenko, Gary D. Pipes et al. · Journal of Pharmaceutical Sciences · 2007 · 103 citations

Igg Molecules, Engineering, Biochemistry +13