Concepedia

Co-treatment with vorinostat synergistically enhances activity of Aurora kinase inhibitor against human breast cancer cells

Warren Fiskus, Stacey L. Hembruff, Rekha Rao, Priyanka Sharma, Ramesh Balusu, Sreedhar Venkannagari, Jacqueline E. Smith, Karissa Peth, Stephen C. Peiper, Kapil N. Bhalla

Breast Cancer Research and Treatment · 2012 · 29 citations · 31 references

DOI

Concepts

References

31

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

Ting‐Chao Chou, Paul Talalay · Advances in Enzyme Regulation · 1984 · 7.2K citations

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Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

Hongyi Zhou, Jian Kuang, Ling Zhong et al. · Nature Genetics · 1998 · 1.3K citations

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VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

Elizabeth A. Harrington, David Bebbington, Jeffrey R. Moore et al. · Nature Medicine · 2004 · 954 citations · Full text

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Phase I Study of an Oral Histone Deacetylase Inhibitor, Suberoylanilide Hydroxamic Acid, in Patients With Advanced Cancer

William Kevin Kelly, Owen A. O’Connor, Lee M. Krug et al. · Journal of Clinical Oncology · 2005 · 907 citations · Full text

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Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

Nagma Khan, Michael Jeffers, Sampath Kumar et al. · Biochemical Journal · 2007 · 710 citations · Full text

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