Use of Primary Cultures of Rat Hepatocytes to Predict Toxicity in the Early Development of New Chemical Entities

Rapid colorimetric assay for cell growth and survival

François Denizot, Rita Lang · Journal of Immunological Methods · 1986 · 4.9K citations

Life Sciences, Biochemistry, Cell Biology +13

Characterization of the Cellular Reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): Subcellular Localization, Substrate Dependence, and Involvement of Mitochondrial Electron Transport in MTT Reduction

Michael V. Berridge, An S. Tan · Archives of Biochemistry and Biophysics · 1993 · 1.4K citations

Life Sciences, Biochemistry, Cell Biology +15

MEIC—A new international multicenter project to evaluate the relevance to human toxicity of in vitro cytotoxicity tests

Inger Bondesson, Björn Ekwall, Sven Hellberg et al. · Cell Biology and Toxicology · 1989 · 179 citations

Pharmacy, Toxicology, Pharmaceutical Toxicology +7

An evaluation of three In vitro cytotoxicity assays

Rosemary Riddell, Richard H. Clothier, Michael Balls · Food and Chemical Toxicology · 1986 · 176 citations

Dentistry, Toxicology, Toxicokinetics +4

Toxicology investigations with cell culture systems

Annalaura Stammati, Vittorio Silano, Flavia Zucco · Toxicology · 1981 · 98 citations

Pharmacy, Cell Biology, Toxicology +12