Concepedia

Publication | Open Access

IL‐22 and IL‐22 binding protein (IL‐22BP) regulate fibrosis and cirrhosis in hepatitis C virus and schistosome infections

DOIFull Paper Access

75

Citations

35

References

2014

Year

Mathieu Sertorio, Xunya Hou, Rodrigo Feliciano do Carmo, Hélia Dessein, Sandrine Cabantous, Mohammed Abdelwahed, Audrey Romano, Fernanda Martins de Albuquerque, Luydson Richardson Silva Vasconcelos, Theomira M. Carmo,
Hepatology

Abstract

These results provide strong evidence that IL-22 protects against and IL-22BP aggravates liver fibrosis and cirrhosis in humans with chronic liver infections. Thus, pharmacological modulation of IL-22 BP may be an effective strategy to limit cirrhosis.

References

YearCitations

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