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Active site-directed antibodies identify calpain II as an early-appearing and pervasive component of neurofibrillary pathology in Alzheimer's disease

Alzheimer's DiseaseMedicineDementiaNeurofibrillary PathologyPathologyDegenerative PathologyNeurochemical BiomarkersProtein MisfoldingNeuroscienceNeurologyNeurodegenerationBrain PathologyNeuropathologyNeuroimmunologyActive Site-directed AntibodiesCalpain Ii