Concepedia

Liver-specific microRNA-122 target sequences incorporated in AAV vectors efficiently inhibits transgene expression in the liver

Z Yuan, J Li, Bo He, Hui Zheng, Christine Mayer, J Li, X Xiao

Gene Therapy · 2010 · 157 citations · 52 references

DOI

Concepts

References

52

Identification of Novel Genes Coding for Small Expressed RNAs

Mariana Lagos‐Quintana, Reinhard Rauhut, Winfried Lendeckel et al. · Science · 2001 · 4.9K citations · Full text

, , +16

Mammalian microRNAs predominantly act to decrease target mRNA levels

Huili Guo, Nicholas T. Ingolia, Jonathan S. Weissman et al. · Nature · 2010 · 3.9K citations · Full text

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Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis

Albert M. Maguire, Francesca Simonelli, Eric A. Pierce et al. · New England Journal of Medicine · 2008 · 2.1K citations · Full text

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Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Catherine S. Manno, Glenn F. Pierce, Valder R. Arruda et al. · Nature Medicine · 2006 · 2.1K citations

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Production of High-Titer Recombinant Adeno-Associated Virus Vectors in the Absence of Helper Adenovirus

Xiao Xiao, Juan Li, R. Jude Samulski · Journal of Virology · 1998 · 1.4K citations · Full text

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