Increased somatic recombination in methylation tolerant human cells with defective DNA mismatch repair

MUTATIONS OF BACTERIA FROM VIRUS SENSITIVITY TO VIRUS RESISTANCE

S. E. Luria, M. Delbrück · Genetics · 1943 · 3.9K citations

Viral Evolution, Genetics, Pathogenesis +9

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

Richard Fishel, Mary Kay Lescoe, Manchanahalli R. Satyanarayana Rao et al. · Cell · 1993 · 2.9K citations

Medicine, Genetics, Pathology +6

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

Yurij Ionov, Miguel A. Peinado, Sergei Malkhosyan et al. · Nature · 1993 · 2.7K citations

Somatic Variant, Tumor Heterogeneity, Ubiquitous Somatic Mutations +6

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

Fredrick S. Leach, Nicholas C. Nicolaides, Nickolas Papadopoulos et al. · Cell · 1993 · 2.3K citations

Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer

Christian Bronner, Sean M. Baker, Paul T. Morrison et al. · Nature · 1994 · 2.1K citations

Genome Instability, Somatic Variant, Genetics +5