Glucose-deprived HT-29 human colon carcinoma cells are sensitive to verrucosidin as a GRP78 down-regulator

The unique physiology of solid tumors: opportunities (and problems) for cancer therapy.

Jeremy Brown, Amato J. Giaccia · PubMed · 1998 · 1.5K citations

Medicine, Oncology, Pharmacology +16

Identification of the cis-Acting Endoplasmic Reticulum Stress Response Element Responsible for Transcriptional Induction of Mammalian Glucose-regulated Proteins

Hiderou Yoshida, Kyosuke Haze, Hideki Yanagi et al. · Journal of Biological Chemistry · 1998 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Endoplasmic Reticulum Chaperone Protein GRP78 Protects Cells from Apoptosis Induced by Topoisomerase Inhibitors

Ramachandra K. Reddy, Changhui Mao, Peter Baumeister et al. · Journal of Biological Chemistry · 2003 · 692 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis

Masahiro Shuda, Nobuo Kondoh, Nobuo Imazeki et al. · Journal of Hepatology · 2003 · 515 citations

Medicine, Molecular Biology, Oncology +13

The Endoplasmic Reticulum Stress-Responsive Protein GRP78 Protects Neurons Against Excitotoxicity and Apoptosis: Suppression of Oxidative Stress and Stabilization of Calcium Homeostasis

ZaiFang Yu, Hong Luo, Weiming Fu et al. · Experimental Neurology · 1999 · 440 citations

Life Sciences, Biochemistry, Neuroscience +14