Bis(O,O-diisopropoxy phosphinothioyl) disulfide - a highly efficient sulfurizing reagent for cost-effective synthesis of oligo(nucleoside phosphorothioate)s

Anti-cancer Drug Design

M SISSAOUI · Archives of Clinical Microbiology · 2018 · 1.4K citations

Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo

Michael Simons, Elazer R. Edelman, Jean-Luc DeKeyser et al. · Nature · 1992 · 736 citations

Life Sciences, Molecular Biology, Pharmacology +8

3H-1,2-Benzodithiole-3-one 1,1-dioxide as an improved sulfurizing reagent in the solid-phase synthesis of oligodeoxyribonucleoside phosphorothioates

Radhakrishnan P. Iyer, William Egan, Judith B. Regan et al. · Journal of the American Chemical Society · 1990 · 301 citations

Natural Sciences, Biochemistry, Chemistry +12

Automated solid-phase synthesis, separation, and stereochemistry of phosphorothioate analogs of oligodeoxyribonucleotides

Wojciech J. Stec, Gerald Zon, William Egan · Journal of the American Chemical Society · 1984 · 275 citations

Natural Sciences, Chemistry, Bioorthogonal Chemistry +10

Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligodeoxynucleotide against rev (art/trs) in chronically infected cells.

Makoto Matsukura, Gerald Zon, Kazuo Shinozuka et al. · Proceedings of the National Academy of Sciences · 1989 · 263 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17